B1UP has 2 places you can enter a SQL username/password. None of these two places require it to be the SA password.
1. On the server component
The server component is optional so you might not have it installed but if you do and you change the password entered there you need to rerun the server component wizard and you should be ready to go again.
2. In the main config.
This is optional unless you use our Crystal Report Features (in which case it is mandatory). If you change the password you need to go to the main config (http://help.boyum-it.com/B1UP/otheroptions.html) and change to the new password via the "Set database information button" (or depending on what version and features turned on it might even prompt you to set the new password)
NB: This is something you need to change for each SAP database