In some cases, the Print Preview and the PDF created by B1 Print & Delivery by the same Report Configuration and Crystal Definition don't look the same.
The Layout can be affected by the Printer Setting in the Crystal Report that should be set to no printer, what font is used (not all are supported in PDF), and Adobe Readers settings.
Ultimate B1UP has no control over this. We can only call the Crystal Report API.
All users would see the same issues if they used out-of-the-box Crystal Integration with SAP (the preview Crystal Report tool from SAP and their PDF button).