This error during the CRM server component indicate that something went wrong connection to SAP’s DI-API. Please press back at the topleft and verify that the server login information are correct. If they are there might be something wrong with the DI-API.
Best way to verify this is to install SAP’s Data Transfer Workbench (DTW) tool. This tool also do DI-API connections and if this can’t connect either there is a general problem that need SAP Supports involvement.